An efficient pipeline for ancient DNA mapping and recovery of endogenous ancient DNA from whole‐genome sequencing data

Ancient DNA from Human and Animal

Research on ancient DNA (aDNA) has the potential to enable molecular biologists and archeologists to decipher certain aspects of history by direct looking into the past. However, several major problems in this field limit the applicability of aDNA studies, most importantly contamination with modern DNA and postmortem DNA degradation. In this study we extracted and analyzed aDNA obtained from ~3...

ancient dna from human and animal

research on ancient dna (adna) has the potential to enable molecular biologists and archeologists to decipher certain aspects of history by direct looking into the past. however, several major problems in this field limit the applicability of adna studies, most importantly contamination with modern dna and postmortem dna degradation. in this study we extracted and analyzed adna obtained from ~3...

Extraction and Analysis of Ancient DNA from Human Remains of Masjede Kabood Burial Site

Ancient DNA

Ancient DNA is a field of molecular evolutionary biology that usesDNA sequence data recovered frompoorly preserved organisms, usually deceased for hundreds to hundreds of thousands of years. Ancient DNA data can provide unique snapshots in time to better understand how populations and species evolve. The field was born in the early 1980s,when thefirst ancientDNAsequences were recovered from pre...

Ancient mitochondrial DNA from hair

The DNA content of hair [1,2] is typically low compared to other tissues, as hair cells undergo dehydration and catabolic breakdown of nucleic acids and organelles during keratinisation [3]. As a consequence, ancient hair specimens have not been widely used as a source of ancient DNA. However, mitochondrial DNA (mtDNA) has been extracted from degraded and old hair samples, including burnt speci...